List of drugs used to treat the medical condition called type 2 diabetes. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. New drugs in development for the treatment of diabetes diabetes. Use this theme for presentations on health care, medicine and drugs misuse, the pharmaceutical industry, etc. Patients with type 2 diabetes t2d typically use several drug treatments during their lifetime. Medications staying up to date with the latest blood glucoselowering medications is an important part of diabetes management. Medication use for the treatment of diabetes in obese individuals. Standards of medical care in diabetes2019 abridged for. Sulfonylureas and the risks of cardiovascular events and. In response, a coauthor of the acp statement observed that other guidelines have also not specifically accounted for these newer medications in their.
People with either type of diabetes also need to manage their diet and physical activity. Here is a selection of some top type 2 diabetes treatments and their latest breakthroughs. Weight loss for obese individuals with diabetes has many health benefits, often leads to improvement in glucose control and sometimes, in type 2 diabetes, near normalisation of abnormal glucose metabolism. New recommendations classification and diagnosis of diabetes. For all new development programs for drugs to treat diabetes, phase 3 studies should be sized to. Global industry analysis and forecast to 2025 the new oral antidiabetic drug market report offers a comprehensive study of the present scenario of the market coupled with major market dynamic. Recent randomized trials have compared the newer antidiabetic agents to treatments involving sulfonylureas, drugs associated with increased cardiovascular risks and mortality in some observational studies with conflicting results. There is an enormous pipeline of drugs and products for the management of diabetes and related comorbidities.
With the exceptions of insulin, exenatide, liraglutide and pramlintide, all are administered orally and are thus also called oral hypoglycemic agents or oral antihyperglycemic agents. These are the recommended screening guidelines for all providers to use whenever a patient is prescribed a sga. Five diabetes drugs in top10 selling list times of india. Effectiveness and safety of newer antidiabetic medications. New treatment for diabetes mellitus and drugs to treat. Many type 2 cases can be controlled by diet, reduction in body weight and appropriate exercise supplemented, if required, by oral hypoglycaemics. Free download diabetes mellitus powerpoint presentation slides. New and emerging drugs and targets for type 2 diabetes. Generally, an ebook can be downloaded in five minutes or less. Notably, patients with type 2 diabetes mellitus t2dm are partially. Ada 2020 standards of care incorporate cvd risk stratification, new medications endocrinology advisor free and ada releases 2020 standards of medical care in diabetes university of north carolina at chapel hill school of medicine free see also. Newer insulin regimens in diabetes postgraduate medical journal. Ppt antidiabetic drugs powerpoint presentation free. Check out our comprehensive chart to understand how your meds work, and keep the list handy for times when your health care provider suggests changes to your treatment plan.
The 2020 standards of medical care in diabetes includes all of adas current clinical practice recommendations and is intended to provide clinicians, patients, researchers, payers, and others with the components of diabetes care, general treatment goals, and tools to evaluate the quality of care. This ppt covers recently fda approved treatment of dm and other drugs that are in clinical pipelines or still under consideration. Chapter 5 drugs for diabetes mellitus 1 chapter 5 drugs for diabetes mellitus 2 diabetes mellitus. For example, glimepiride and the dpp4 inhibitor linagliptin showed similar clinical efficacy over 2 years difference in hba 1c concentration 020%, 975% ci 009030, meeting the predefined noninferiority criteria.
Jan 23, 2019 this medicine ppt template includes four readymade content slides that you can modify in the slide master view in powerpoint. Oral hypoglycemics and insulin free powerpoint templates page 1 2. Antidiabetic drugs are medicines developed to stabilise and control blood glucose levels amongst people with diabetes. Diabetes medication pharmacology bja education oxford. Diabetic kidney disease and diabetic nephropathy are the leading cause of endstage kidney disease in the united states and most developed countries. Also, it highlights the indepth market analysis with the latest trends, drivers and its segments with respect to regional and country. Diabetes mellitus is a condition in which the body cannot effectively regulate blood glucose or blood sugar. Antidiabetic drugs are medications used to treat diabetes mellitus by lowering blood glucose levels.
In addition to new dipeptidyl peptidase4 inhibitors, glucagonlike peptide 1 analogs, thiazolidinediones, glinides, and new insulin formulations, there are also unique peroxisome proliferatoractivated receptor agonists, selective sodium glucose cotransporter 2 inhibitors, and several other. Diabetes accounts for 30% to 50% of the incident cases of endstage kidney disease in the united states. The legacy effect of early good glycaemic control in people with diabetes shows it is associated with reduction of microvascular and macrovascular complications. New drug treatments versus structured education programmes for type 2 diabetes. In recent studies comparing sulphonylureas with newer drugs, durability has been found for up to 2 years. Noninsulin injectables new drugs are available for people with type 2 diabetes. Aug 25, 2015 uses of insulin diabetes mellitus insulin is effective in all forms of diabetes mellitus and is a must for type 1 cases, and gestational diabetes.
The adobe flash plugin is needed to view this content. Insulin therapy is essential and lifesaving in individuals with type 1 diabetes and beneficial for those with type 2 diabetes who fail to achieve optimal glycaemic targets with other classes of glucoselowering therapies. There is a theoretical risk of immunodeficiency and exacerbation of infections 42 with these drugs, however, which prevent them from being used as first line drugs in hiv. Comparative effectiveness and safety of medications for type 2 diabetes. Compare and contrast the differences between the drug therapy recommendations of several of the lat est and leading diabetes guidelines. Uses of insulin diabetes mellitus insulin is effective in all forms of diabetes mellitus and is a must for type 1 cases, and gestational diabetes.
Practice guidelines resources american diabetes association. This algorithm for the comprehensive management of persons with type 2 diabetes t2d was developed to provide clinicians with a practical guide that considers the whole patient, his or her spectrum of risks and complications, and evidencebased approaches to treatment. Ppt antidiabetic drugs powerpoint presentation free to. The new drug lixisenatide adlyxin offers a once a day injection option in type2 diabetes patients. Click on the drug to find more information including the brand names,dose,sideeffects, adverse events, when to take the. Insulin pramlintide amylin glp1 receptor agonists such as byetta and victoza oral hypoglycemics tablets antidiabetic drugs for type 1 diabetes. Although initially designed to evaluate safety, some of these cvd outcome trials cvots have in fact shown cvd benefits. New drugs for the treatment of diabetes mellitus circulation. Sep 29, 2014 as many as 14 classes of drugs are currently available for the treatment of type 2 diabetes mellitus. Diabetes a chronic metabolic disorder characterised by a high blood glucose concentration hyperglycaemia fasting plasma glucose 7. Food and drug administration fda continues to approve and improve type 2 diabetes medications and ease dosing regimens for patients.
Effective strategies for identifying an eating disorder and navigating treatment options for patients with type 1 diabetes and an eating disorder eddmt1 oral antihyperglycemic and insulin therapies in pregnancy. All these agents aim to reduce blood sugar levels to an acceptable range called achieving normoglycemia and relieve symptoms of diabetes such as thirst, excessive urination, and ketoacidosis a serious complication of diabetes that occurs when the body cannot use. Drugs used in diabetes treat diabetes mellitus by lowering the glucose level in the blood. Antidiabetic agents refer to all the different types of medicine involved in the treatment of diabetes. Patients may report a predominance of diarrhea ibsd or constipation ibsc, but both may occur in an individual patient. List of drugsmedicine used for type 2 diabetes diabetes. Assess the differences in incretinbased therapies for the treatment of type 2 diabetes mellitus t2dm. Standards of medical care in diabetes 2020 abridged for primary care. Cardiovascular outcome trials of the newer antidiabetic. Intensive material on diabetes, types, new concepts, its existing therapy, recent advances and future prospects. If so, share your ppt presentation slides online with. Diabetes global scenario 2015 2040 world 416 million world 642 million people living with diabetes middle east and north africa 85% south east asia 64% south and central america 55% western pacific 46% north america and caribbean 30% europe 33% africa 93% 54% the idf atlas, 7th edition, 2015. Ppt chapter 5 drugs for diabetes mellitus powerpoint. See also our medical powerpoint template with the same color palette.
Consensus development conference on antipsychotic drugs and obesity and diabetes. These 3 new drug categories have further expanded treatment options in patients with t2dm see table 1. Almost 300 companies are involved in developing drugs for type 2 diabetes alone, and additional companies are working on type 1 diabetes and diabetes complications. Download ppt quality assurance and criteria are more specific for drugs and devices than for complex interventions such as dsme, which might help to account for the perceived lack of value by healthcare. Near term there are no new classes of antihyperglycemic. Polycystic ovary syndrome pcos is the most common endocrinopathy in women of reproductive age, with an approximate prevalence of 610 %. There is a debate about the best secondline therapy after metformin monotherapy failure due to the increasing number of available antidiabetic drugs and the lack of comparative clinical trials of secondary treatment regimens. Data sources include ibm watson micromedex updated 4 may 2020, cerner multum updated 4 may. Albiglutide tanzeum dulaglutide trulicity extended. Advances in treatment options for polycystic ovary syndrome.
While prior research compared the costeffectiveness of two alternative. Psap 20 ewharmrcoethrpwatrmrco 5 new pharmacotherapies for type 2 diabetes learning objectives 1. Welcome to our new report, advancing health through innovation. Download free powerpoint themes and powerpoint backgrounds for your presentations. Diabetes in check designed by a certified diabetes educator offers digital coaching from a certified diabetes educator app claims to help individuals get active, eat better, and control their weight able to send data quickly to healthcare provider community message boards with over 200,000 people living with type 2 diabetes. Guideline for the management of heart failure focused update date. Ppt newer diabetes medications, powerpoint presentation. Metformin for the prevention of type 2 diabetes january 2020 in a metaanalysis of randomized trials of metformin for the prevention of type 2 diabetes in highrisk individuals, metformin decreased the incidence of newonset diabetes compared with standard diet and exercise but not compared with intensive diet and exercise.
In spite of all the experimental and clinical work on diabetes which has been done in the past years, a specific or etiologic treatment has not been attained. May 14, 2017 obesity is a major cause of type 2 diabetes and may complicate type 1 diabetes. Weight loss is difficult to maintain and attempts to lose weight may be undermined by some diabetes treatments. View and download powerpoint presentations on new treatment options for diabetes ppt. In response to the type 2 diabetes epidemic, the u. Many people with type 2 diabetes take glucoselowering medications which can be taken orally or by injection. These medicines are most often used to treat type 2 diabetes. American association of clinical endocrinologists, north american association for the study of obesity. People with type1 diabetes must always have a constant source of exogenous insulin, otherwise diabetic ketoacidosis dka will result.
Jan 19, 2019 the costs to the uks national health service nhs for treating diabetes took prominence in the media in november, 2018, as the nhs bill for blood glucoselowering drugs for the first time surpassed. Online price comparison januvia sitagliptin januvia with or alone in conjunction with other prescription drugs that can be purchased from an online reliable canadian pharmacy such as insulin, glimepiride, metformin, or pioglitazone with sufficient diet and exercise to control high blood sugar levels caused by type 2 diabetes. New drugs for the treatment of diabetes circulation aha journals. For all new development programs for drugs to treat diabetes, phase 3 studies should be sized to allow meaningful evaluation of the consistency of effects across subgroups based on sex, age. New diabetes drugs dpp4 inhibitors exenatide is the property of its rightful owner.
Comprehensive type 2 diabetes management algorithm 2020. The costs of drug prescriptions for diabetes in the nhs the. The types of diabetes there are two types of diabetes one is type 1 diabetes the other is type 2 diabetes 3. Management of diabetes mellitus linkedin slideshare. Jan 14, 2011 the newer class of oads, the polypeptide protease iv inhibitors, ie, saxagliptin, sitagliptin, and vildagliptin, have not been studied in patients with hiv and diabetes. In brief a variety of new agents are in development for the treatment of type 1 or type 2 diabetes.
Some recent reports provide listings of 221 companies with development programs in type 2 diabetes alone. Irritable bowel syndrome ibs is a chronic, relapsing functional gastrointestinal gi disorder. A free powerpoint ppt presentation displayed as a flash slide show on id. Diabetes mellitus notes for medical students and mbbs doctors. Diabetes is a chronic lifelong disease marked by high levels of sugar in the blood.
Gadgets, gizmos, and apps american diabetes association. Antidiabetic drugs are commonly used to manage diabetes there are a number of different types of antidiabetic drug including. Do sulphonylureas still have a place in clinical practice. New drug approvals and other drug therapy advances of 2017. Since the late 1990s, however, several new classes of agents have been approved for use in type 2 diabetes, with more in development. Find powerpoint presentations and slides using the power of, find free presentations research about new treatment options for diabetes ppt. New drugs in development for the treatment of diabetes. New treatment options for diabetes ppt xpowerpoint. New drug treatments versus structured education programmes. This is attributed to the increased prevalence of diabetes and the increased cost per person with diabetes. Top 8 breakthrough diabetes treatments you may have missed. Diabetes mellitus overview and treatments andrew p. Pramlintide symlin, exenatide byetta, and liraglutide victoza are noninsulin injectable drugs. Concerns of elevated cardiovascular disease cvd risk with some antidiabetic medications warranted phase 4 clinical trials to demonstrate cvd safety of newly marketed antidiabetic drugs.
Many youth with type 2 diabetestake insulin, often in addition to other glucose lowering medications. The chronic care model ccm is an effective framework for improv. There are different classes of antidiabetic drugs, and their selection. A striking advance has been made in dietetic treatment, however, and, with the clearer and more detailed knowledge of the metabolic. Lecture 14 chapter 46 antidiabetic drugs antidiabetic drugs drugs used to control diabetes mellitus a chronic disease that affects carbohydrate metabolism 2 groups. Ppt newer diabetes medications, powerpoint presentation free to download id. In perhaps a grim reminder of the growing incidence of lifestyle diseases, five out of the top 10 largestselling drugs in the country are now anti diabetes, with the therapy registering a. Recent advances in the treatment of diabetes mellitus slideshare. Hypoglycemia is the most common side effects for most glucoselowering therapies. Several additional studies have assessed vildagliptin as monotherapy in comparison with other oral antidiabetic agents, including acarbose, metformin.
Diabetes mellitus dm is characterized by elevated blood sugar levels due to absolute or relative lack of insulin. All these agents aim to reduce blood sugar levels to an acceptable range called achieving normoglycemia and relieve symptoms of diabetes such as thirst, excessive urination, and ketoacidosis a serious complication of diabetes that occurs. Presentation slides american association of diabetes. Although this represents a significant public health concern, it is important to note that only 30% to 40% of patients with diabetes develop.
As many as 14 classes of drugs are currently available for the treatment of type 2 diabetes mellitus. The uploader spent hisher valuable time to create this diabetes mellitus powerpoint presentation slides, to share hisher useful content with the world. Guidance for industry food and drug administration. It constitutes a serious risk that faces diabetic patients who fast during ramadan the 9th month in the islamic calendar. People with type 2 diabetes can be managed either with diet alone, or a combination of diet and noninsulin glucose lowering drugs. The different kinds of diabetes medicines are listed on the next few pages. The advent of a new class of drugs known as biologics has revolutionized the treatment of rheumatoid arthritis ra. New glucoselowering classes like dipeptidyl peptidase4 dpp4 inhibitors, glucagonlike peptide 1 receptor agonist glp1 ra, and sodiumglucose cotransporter2 sglt2 inhibitors are. A free powerpoint ppt presentation displayed as a flash slide show on. Newer drugs with a positive outcome on heart disease and death, improved monitoring devices and an understanding of how diet and exercise impact diabetes is adding up to a gain in outcomes for patients.